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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0494
All Species:
18.48
Human Site:
S435
Identified Species:
58.1
UniProt:
O75071
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75071
NP_055589.1
495
55031
S435
I
S
L
P
G
V
S
S
T
E
D
L
Q
D
L
Chimpanzee
Pan troglodytes
XP_524573
699
75450
S639
I
S
L
P
G
V
S
S
T
E
D
L
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001096587
383
42258
P326
K
P
E
S
N
R
P
P
A
T
A
D
E
E
Q
Dog
Lupus familis
XP_539624
565
62275
S505
V
V
L
P
G
I
S
S
I
Q
D
L
Q
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGQ6
484
53675
S424
L
S
L
P
G
I
S
S
I
K
D
L
Q
D
L
Rat
Rattus norvegicus
NP_001100147
484
53459
S424
I
S
L
P
G
I
S
S
I
K
D
L
Q
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087373
461
50310
E404
I
S
T
E
K
D
L
E
D
L
F
S
R
S
V
Zebra Danio
Brachydanio rerio
NP_996958
255
27034
S198
K
S
V
A
S
I
G
S
T
V
T
S
V
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
69.9
76.4
N.A.
79.3
82.4
N.A.
N.A.
N.A.
48.6
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.5
73.3
82.3
N.A.
89.6
90.5
N.A.
N.A.
N.A.
64.6
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
66.6
N.A.
73.3
80
N.A.
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
13
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
13
0
63
13
0
63
0
% D
% Glu:
0
0
13
13
0
0
0
13
0
25
0
0
13
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
0
63
0
13
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
50
0
0
0
0
50
0
0
38
0
0
0
0
0
0
% I
% Lys:
25
0
0
0
13
0
0
0
0
25
0
0
0
0
0
% K
% Leu:
13
0
63
0
0
0
13
0
0
13
0
63
0
0
63
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
63
0
0
13
13
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
0
63
13
13
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
75
0
13
13
0
63
75
0
0
0
25
0
13
0
% S
% Thr:
0
0
13
0
0
0
0
0
38
13
13
0
0
0
0
% T
% Val:
13
13
13
0
0
25
0
0
0
13
0
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _